The Grand Duke of Jupiter can cause a lot of trouble with work, health, relations, etc if the area is disturbed or faced while working, eating and sleeping with our head pointing in that direction. While it is okay to have your back at this direction, avoid facing it.
The location of the Tai Sui changes every year. In the Yang Fire Monkey year of 2016, the Tai Sui is in the South West 3 sector – location between 232.5º – 247.5º. You can appease the Grand Duke by placing a Pi Yao in this direction with his back towards it and another in the exactly opposite direction in your space looking at it. Avoid breaking ground or generally disturbing this area.
If construction needs to be done, use a Feng Shui Consultant who can help with good date selection to start renovations.